Hericor-MRL

Developed by the United Kingdom based Mycology Research Laboratories Ltd ( www.mycologyresearch.com ), Hericor-MRL is a combination product that supports the repair of intestinal "villi", which are responsible for effective absorption of nutrients in the small intestine. 

 

Enzyme Nutrition to Maintain

Healthy Digestive System

What is Hericor-MRL?

Hericor-MRL is a powder combination of two mushroom biomasses ( Coriolus versicolor (50%) and Hericium  erinaceus (50%)), jointly providing three important enzyme functions that promote healthy digestion. The functions are:

 

Enzymes that prevent oxidative stress

 

-Lacasse actitivty

-Superoxide Dismutase (SOD) activity

 

Enzymes that prevent celluar growth

 

-Protease activity

-Glucoseamylase activity

 

Enzyme that promote detoxification

 

-Peroxidase activity

-Cytochrome P-450 activity

-Cytochrome P-450 reductase activity

 

The combined effect of the aformentioned eznyme activities is the promotion of the healty digestive system that may be compromised when the digestive "villi" are not functioning in a proper fashion.

 

What is the role of "villi" in the digestive system and presence in small versus large intestine?

 

The nutrient absorption in the small intestine is conducted by the "villi". The villi are microsopic intrusions into the small intestine which are covered by with epithelial cells respnsible for the absorption of nutrients and transfer them into the blood stream. These epithelial cells have a lifespan of three to five days and require enzyme support to assist in their replacement.

 

The large intestine does not contain "villi" but handles the absorption of water and bacteria.

 

Which digestive disorders can compromise the function of the “villi” in the small intestine?

Digestive systems are compromised by disorders like:

Þ coelaic disease

Þ Crohn´s disease

Þ ulcerative colitis

Þ irritable bowel disease (IBS)

These disorders reduce the vital surface area of absorptive cell area of the “villi” and have a damaging effect on the digestive system.

 

How can enzyme therapy in the form of Hericor-MRL maintain healthy digestive function?

a) Reducing oxidative stress caused by compromised "villi".

b) Increasing detoxificaiton of the digestive tract.

c) Inhibiting those cellular factors responsible for compromising the "villi".

 

 

Besides Hericor-MRL supporting a healthy digestive function what other studies have been conducted with reference to the ingredients? 

 a)            Reduction in neuroinflammation:

1.  A. Trovato, R. Siracusa , R. Di Paola , M. Scuto, V. Fronte, G. Koverech, M. Luca a, A. Serra b, M.A. Toscano a, A. Petralia b, S. Cuzzocrea c, V. Calabrese, Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer’s disease pathogenesis. Neurotoxicology. 2016 Mar; 53:350-358.

 https://www.ncbi.nlm.nih.gov/pubmed/2643

2.  A. Trovato, R. Siracusa, R. Di Paola, M. Scuto, M. L. Ontario, Ornella Bua1, Paola Di Mauro, M. A. Toscano, C. C. T. Petralia, L. Maiolino, A. Serra, S. Cuzzocrea and Vittorio Calabrese.  Redox modulation of cellular stress response and lipoxin A4 expression by Hericium erinaceus in rat brain: relevance to Alzheimer’s disease pathogenesis. Immunity & Ageing (2016) 13:23.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938991/

 

 b)            Increase in neurogenic reserve:

1.       Ferreiro E , Pita IR , Mota SI , Valero J , Ferreira NR , Fernandes T , Calabrese V , Fontes-Ribeiro CA , Pereira FC , Rego AC. Coriolus versicolor biomass increases dendritic arborization of newly generated neurons in mouse hippocampal dentate gyrus. Oncotarget. 2018 Aug 31;9(68): 32929-32942.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152478/

c)             Prebiotic Activity 

1.       Ferrão J, Bell V, Calabrese V, Pimentel L, Pintado M, Fernandes TH. Impact of mushroom nutrition on microbiota and potential for preventative health.  Journal of Food and Nutrition Research 2017;5(4):226–3.

 http://pubs.sciepub.com/jfnr/5/4/4/index.html

What is the supplementation schedule for Hericor-MRL?

The supplementation schedule assumes a 65 kgs person and the supplementation is the following: 

 

  Week

1

2

3

4

5

6

7

8

Total

 

 

 

 

 

 

 

 

 

 

Hericor-MRL

 

 

 

 

 

 

 

 

 

4 g/day

4g

4g

4g

4g

4g

4g

4g

4g

200 g

 

 

 

 

 

 

 

 

 

 

Spoons

2

2

2

2

2

2

2

2

 

morning

 

 

 

 

 

 

 

 

 

 It is recommended that Hericor-MRL® is taken at breakfast and mixed with yogurt or cereal. It is not recom-mended to take with citric juices as this will deplete the enzyme activity of the product.

 In 5% of cases, Hericor-MRL® may provoke a diarrhoea, which if persists after 5 days, the use of Hericor-MRL® should be discontinued

When taken with Speak, it is recommended that Hericor-MRL should be taken for one week prior to commencing Speak supplementation to increase the efficacy of Speak supplementation.

Packing Hericor-MRL

 

250 g biomass powder of Coriolus versicolor (50%) and Hericium erinaceus (50%) with 2 g spoon.*

 

References: 

 

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